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In 1998, Celera Genomics challenged the publicly funded Human Genome Project to sequence the entire human genome faster. Using competing methods — careful BAC mapping versus whole-genome shotgun sequencing — both sides accelerated toward a draft. A working version was announced in 2000, detailed papers followed in 2001, and the data helped transform disease research while driving sequencing costs from about $100 million to roughly $1,000 per genome. #HumanGenomeProject #DNA #Genetics #ScienceFac
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Shotgun Sequencing: The Scientific Gamble That Changed Genomics Forever
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