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Polysorbate 80 is particularly significant in the context of treating toxoplasmosis, a parasitic infection caused by *Toxoplasma gondii*, which can lead to severe neurological complications, especially in immunocompromised individuals. The blood-brain barrier (BBB) is a formidable obstacle that protects the brain from pathogens and toxins but also poses a challenge for drug delivery. Many antiparasitic medications, such as pyrimethamine and sulfadiazine, are essential for treating toxoplasmosis
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