An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word intron is derived from the term intr agenic regi on, i.e., a region inside …

Here we review evidence from mRNA analysis and entire genomic sequencing indicating that pathogenic mutations can occur deep within the introns of over 75 disease-associated genes.

3 days ago · Introns may contain sequences that regulate how genes are expressed or transcribed and how mRNA is processed.

Jul 15, 2019 · Intronic variation is highly common, but the majority of variants have no effect. This article describes cases where variants lead to disease.

Introns are non-coding, self-splicing intragenic stretches of DNA that are transcribed (code for RNA) but are spliced after transcription (Edgell et al., 2000). Frequency of introns in bacteria …

Jun 29, 2025 · Exons are the protein-coding sequences, while introns are non-coding segments interspersed between them. An intronic variant is a change in the DNA sequence that occurs …

Definition of 'intronic' intronic adjective biochemistry (of a stretch of DNA) interrupting a gene and not contributing to the specification of a protein

Introns are also referred to as intervening sequences. Introns are non-coding sections of an RNA transcript, or the DNA encoding it, which are spliced out, or removed, before the RNA molecule...

The meaning of INTRON is a polynucleotide sequence in a nucleic acid that does not code information for protein synthesis and is removed before translation of messenger RNA.

Apr 29, 2025 · Many inherited disorders once attributed solely to exonic mutations are now recognized to have intronic variants affecting gene function. In conditions such as cystic …