Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

How do breast cancer cells bypass the blood-brain barrier (BBB) to colonize the brain? This study uncovers a ...

Among the hundreds of proteins that are secreted by Legionella pneumophila (the causative agent of Legionnaires’ disease) ...

Abscisic acid (ABA) prevents cotyledon opening in the dark by modulating splicing through serine/arginine-rich (SR) proteins RS40 and RS41. Light reduces ABA levels, releasing this repression to allow ...

In “Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor” by Singh et al, 2019, and “Transcript-specific induction of stop codon readthrough using a ...

Macrophages not only clean the wound early for repair, but are also critically involved in all subsequent phases of proliferation and regeneration (Mirza et al, 2009; Shook et al, 2016).They ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Interorgan communication is vital for tissue ...

In this study, using C. elegans and human cell lines, we characterized the physiological effects of thiol reductive stress. Because thiol antioxidants result in the increased expression of rips‐1 ...

The ubiquitin system is an integral part of cellular responses to environmental changes. The post‐translational modification of proteins with ubiquitin modulates virtually every cellular pathway and ...

CIITA transcription itself is controlled by a 14 kb multi-promoter regulatory region, containing three independent promoter elements in humans, pI, pIII, and pIV, which are expressed in a ...

Recently, we were able to show that both SARS-CoV-2 infection and mRNA vaccination prime human monocyte-derived macrophages for potent secretion of pro-inflammatory cytokines following restimulation ...