Cincinnati left-hander Nick Lodolo abruptly left Monday night's game against the Chicago Cubs with two outs in the bottom of the second inning with a blister on his left index finger.

The Cincinnati Reds needed five relievers to finish Sunday's suspended Speedway Classic game, then went to the pen in the second inning Monday.

BOTTOM LINE: The Cincinnati Reds lead 1-0 in a three-game series against the Chicago Cubs. Chicago is 35-21 in home games and 65-47 overall. Cubs hitters are batting a collective .254, the fourth-best team batting average in MLB play.

Cincinnati Reds ace Hunter Greene made his third rehab appearance on Sunday and his second with Triple-A Louisville. He gave up two unearned runs on three hits, walked a batter, and struck out seven over 3 1/3 innings. He threw 42 of his 66 pitches for strikes.

The Cubs are favored (-140 moneyline odds) when they host the Reds (+118). The Cubs will give the ball to Mike Soroka (3-8) versus the Reds and Nick Lodolo (8-6). The Cubs won their most recent game against the Orioles yesterday by a 5-3 score.