The brain really is an incredible organ, and neurons are the vital link between, well, everything. The brain is anything but ...

In agreement with this study, glutamate is removed from synaptic cleft by diffusion ... needs to be expanded to incorporate other important features, such as direct neurotransmitter release from ...

During many tasks the brain receives real-time feedback about performance. What should it do with that information, at the synaptic level, so that tasks can be performed as well as possible? The ...

Neuroscientists believe that synaptic plasticity, as these changes are called, plays an important role in storing memories. However, the rules governing when and how much synapses change are not ...

Illustration of neurotransmitters crossing synaptic cleft. Source: BruceBlaus in Wikimedia Commons/Public domain Returning to Graz, Loewi brought back a newfound interest in autonomic function.

Abstract: Molecular communication (MC) within the synaptic cleft is vital for neurotransmitter diffusion, a process critical to cognitive functions. In Alzheimer’s Disease (AD), beta-amyloid oligomers ...

Here we focus on the rapid trafficking of these neurotransmitter receptors and ... AMPARs are probably inserted at sites distant from the synaptic cleft, from which they diffuse laterally within ...

McCabe’s team is interested in a specific part of this structure: the synaptic boutons, zones at the end of neurons where neurotransmitter molecules released by one cell trigger the next cell. In a ...

Once they traverse the gap between neurons (synaptic cleft), neurotransmitters interact with excitatory or inhibitory receptors on the receiving cell to generate excitatory or inhibitory signals.

The existence of a crosstalk between the nervous and immune systems is well established. Neurotransmitters can be produced by immune cells, whereas cytokines can be secreted by cells of nervous ...