Genetic material from hundreds of mammoths is providing an unprecedented glimpse into their family tree and shows how these ...

The following is a summary of “Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations,” ...

A CRISPR/Cas9-based galactose screening identifies key mitochondrial genes involved in OXPHOS and oxidative metabolism, ...

The study tracks mammoth evolution over a million years using mitogenomes, showing shifts in diversity and lineage tied to ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...

We now show that NT induces release of extracellular mitochondrial DNA (mtDNA) that could act as "autoimmune" trigger. We further show that serum from young autistic patients contains mtDNA (n ...

Researchers at the University of Cologne found that mitochondrial dysfunction leads to early skeletal aging by disrupting cartilage metabolism. The study identified maladaptive metabolic shifts, ...

The mitochondrial DNA (mtDNA, green) is ejected from the mitochondria (magenta) and taken up by a lysosome, which contains the retromer (cyan). The highlighted section was also analyzed using 3D ...

Widespread neuronal mitochondrial complex I (CI) deficiency was recently reported to be a characteristic in a subgroup of individuals with idiopathic Parkinson's disease (PD). Here, we sought to ...

The POLG gene regulates the production of DNA polymerase gamma, an enzyme that copies mitochondrial DNA. Without it, the mitochondria cannot function normally and, as a result, fail to provide the ...