Cardiac hypertrophy, as an important pathological change, contributes to heart failure. Recent studies indicate that the mitochondria-associated endoplasmic reticulum membranes (MAMs) play key roles ...

Epilepsy, a complex neurological condition marked by recurring seizures, is increasingly recognized for its intricate relationship with mitochondria, the cellular powerhouses responsible for energy ...

Département de chimie - Faculté des arts et des sciences, Université de Montréal, Campus MIL, 1375, Ave. Thérèse Lavoie-Roux, Montréal, Québec H2V 0B3, Canada ...

Department of Cell Biology, Third Military Medical University, Chongqing 400038, China Department of Pain and Rehabilitation, Xinqiao Hospital, Third Military Medical University, Chongqing 400038, ...

Citation: Newly discovered mechanism of mitochondrial dysfunction in obesity may drive insulin resistance and type 2 diabetes (2025, May 30) retrieved 19 June 2025 from https://medicalxpress.com ...

The mitochondrial calcium uniporter channel (MCUC) mediates mitochondrial calcium entry, regulating energy metabolism and cell death. Although several MCUC components have been identified, the ...

New research published in Nature Communications into hidden mutations in mitochondrial DNA has uncovered how high mutational levels coincide with later life and link to aging markers. Mitochondria ...

A study found that genetic mutations associated with amyotrophic lateral sclerosis (ALS) lead to problems with the function and transport of mitochondria, cellular structures needed for energy ...

Single-cell analysis of over 120,000 cells reveals how mitochondrial DNA mutations accumulate with age and may affect ageing and neurodegeneration. New research published in Nature Communications into ...

People often refer to mitochondria as the powerhouses of the cell. Their main function is to generate the energy necessary to power cells, but they are also involved in cell signaling and death.