Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis. Since ...

A deeper understanding of vitiligo's autoimmune mechanisms has fundamentally transformed vitiligo care, explains Susan Taylor, MD. A deeper understanding of vitiligo's autoimmune mechanisms has ...

Bonnie Blue’s “breeding mission” saw about 400 sign-ups from men, including gay creator Jak White. “It seemed like a fun event,” White, 20, exclusively told Us Weekly on the heels of Blue, 26, ...

A phase 3 rheumatoid arthritis trial of Lynk Pharmaceuticals’ JAK1 inhibitor in China has hit its primary endpoint, boosting the prospects of a candidate designed to avoid the adverse events caused by ...

A “V for Vendetta” TV series is currently in development at HBO, Variety has learned exclusively. According to sources, Pete Jackson is attached to write the series adaptation. James Gunn and Peter ...

American youngster Jak Crawford has inched closer to a Formula 1 drive by stepping up to the role of Aston Martin’s reserve driver. Crawford, 20, joined Aston Martin’s young driver development program ...

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For much of the 2025 season, Jak Crawford has been considered the next American hopeful for Formula One. The last American to compete in the pinnacle of motorsport was Logan Sargeant, who raced for ...

A meta-analysis showed no significant differences between JAK inhibitor use and TNF antagonist use in terms of the risk for serious infections or malignant neoplasms in patients with immune-mediated ...

Maddie Fisher is a writer, journalist and game developer. She was born and raised on the east coast, having started working in games journalism over fifteen years ago. She tends to enjoy musical ...

Please provide your email address to receive an email when new articles are posted on . JAK inhibition carried higher malignancy risk vs. biologic DMARDs. Malignancy risk was seen in older patients ...

Some previous studies, including the ORAL Surveillance randomized trial, have shown moderately greater cancer risks with JAK inhibitors versus TNF inhibitors. But some other analyses of real-world ...