Spatial metabolomics is transforming our understanding of microbial systems by uncovering the localized molecular dynamics ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...

In “Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor” by Singh et al, 2019, and “Transcript-specific induction of stop codon readthrough using a ...

Macrophages not only clean the wound early for repair, but are also critically involved in all subsequent phases of proliferation and regeneration (Mirza et al, 2009; Shook et al, 2016).They ...

In this study, using C. elegans and human cell lines, we characterized the physiological effects of thiol reductive stress. Because thiol antioxidants result in the increased expression of rips‐1 ...

The ubiquitin system is an integral part of cellular responses to environmental changes. The post‐translational modification of proteins with ubiquitin modulates virtually every cellular pathway and ...

CIITA transcription itself is controlled by a 14 kb multi-promoter regulatory region, containing three independent promoter elements in humans, pI, pIII, and pIV, which are expressed in a ...

Recently, we were able to show that both SARS-CoV-2 infection and mRNA vaccination prime human monocyte-derived macrophages for potent secretion of pro-inflammatory cytokines following restimulation ...

Paraneoplastic syndrome represents a diverse array of clinical manifestations occurring in multiple organs of cancer patients, which are not directly attributable to tumor burden or invasion (Kannoth, ...

Astrocytes are generated from radial glial cells (RGCs) in the ventricular zone during brain development (Kriegstein and Alvarez-Buylla, 2009; Lin et al, 2021).In the dorsal neocortex, RGCs express ...

Chloride (Cl −) ions cause major damage to crops in saline soils.Understanding the key factors that influence Cl − uptake and translocation will aid the breeding of more salt-tolerant crops. Here, ...

Given the link to antiviral defenses, viruses have developed strategies to disrupt stress granule formation and even hijacked these factors to facilitate their replication (Eiermann et al, 2020; ...