Abstract: Sequence alignment is a crucial tool in biological research. Alignment quality is typically assessed using scores, but these do not guarantee optimality. Estimating the optimal alignment ...

NEFFy is a versatile and efficient tool for bioinformatics research, offering advanced features for calculating NEFF (Normalized Effective Number of Sequences) for Multiple Sequence Alignments (MSA)s ...

Abstract: We present SegINR, a novel approach to neural Text-to-Speech (TTS) that eliminates the need for either an auxiliary duration predictor or autoregressive (AR) sequence modeling for alignment.

Starting with alignments of contigs to a reference genome, produce a chromosome-scale pseudoassembly by patching gaps between mapped contigs with sequences from the reference. usage: GPatch.py [-h] -q ...