As we age, blood stem cells, the essential source of new blood cells in the body, can accumulate genetic mutations.

Mitochondria play a crucial role in acquiring pluripotency and determining cell fate. The mitochondrial unfolded protein ...

The mutated stem cells also contained turbocharged mitochondria, which gave the cells a strong competitive growth advantage. "This was really unexpected," Trowbridge said. "This gene was not ...

A new study reveals how the Dnmt3a mutation drives blood stem cell overgrowth, contributing to clonal hematopoiesis and ...