Interleukin-7 (IL-7) is required, and limiting, for T-cell development and survival. IL-7 production by stromal cells in lymphoid tissues is constitutive. The amount of available IL-7 is proposed to ...
Class II transactivator (CIITA), a coactivator required for class II major histocompatibility complex (MHC) transcription, is expressed in B cells but extinguished in plasma cells. This report ...
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