The 22nd season of Grey's Anatomy will premiere on ABC on Oct. 9 and be available to stream on Hulu the following day. Episode 1 will cover the aftermath of the OR explosion, and Marinis teased in her interview with Shondaland that it's not clear if everyone survived.

The doctor who perished in the season 22 premiere takes THR behind the scenes of how she found out, what she contributed to her final scenes and shares a message to upset viewers.

While a massive shakeup in Grey’s Anatomy has seen the departure of a major character, it has also resulted in the addition of new players to the Season 22 cast. Trevor Jackson, who made his debut in the fan-favorite medical drama as Dr.