Explore the role of transcription factor biology in drug discovery and how it impacts our understanding of disease mechanisms ...

An error in a gene, a mutation, can cause a disease, but the relationship between the genome of an organism and its physical characteristics, and exactly how genetic ...

Transcription is the process of copying DNA to RNA. The accuracy of transcription processes varies widely among species, across cell types and within distinct regions of the genome, with profound ...

Scientists used the auxin-inducible degron 2 system on CTCF, bringing the novel approach to bear on a fundamental protein. CTCF is a critical protein known to play various roles in key biological ...

DNA, the long polymer curled up inside our cells, is often described as the instructions for life. But those instructions are stored in DNA’s chemical code, and reading that code requires the ...

Eukaryotic transcription is a complicated business. The regulation of gene expression is fundamental to cell survival and its study forms the basis of numerous research programmes. Recent discoveries ...