・A mouse model of tuberous sclerosis complex (TSC) had abnormal dendritic spine morphology and neuronal dysfunction. These abnormalities were rescued by the administration of a Rheb inhibitor. ・This ...
Study in a TSC mouse model further demonstrates simufilam’s anti-seizure activity Study conducted in collaboration with TSC Alliance using a well-accepted Tsc1-knockout model First clinical study for ...
The TSC Preclinical Consortium offers animal models for various manifestations of TSC, including epilepsy. One such model is the Tsc1 conditional knockout mouse line developed by Dr. Michael Wong at ...
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