A small cluster of damaged immune cells can do outsized harm. That is the picture emerging from new research at UCLA, where ...

Cellular senescence is a state characterized by permanent cell-cycle arrest, increased expression of markers such as p16^INK4a and p21^CIP1/WAF1, elevated DNA damage signals (e.g., γ-H2AX) and a ...

Aging is a complex biological process characterized by the progressive decline of physiological integrity, leading to impaired function and increased vulnerability to disease. It is the strongest risk ...

Markers of cellular aging -- such as DNA damage response, cellular senescence, and inflammatory pathways -- significantly increased in all breast cancer survivors, regardless of the type of treatment ...

There exists a complex synergistic relationship among cancer, circadian rhythms, and aging: aging is a major risk factor for cancer, disruption of circadian rhythms promotes tumor initiation and ...

Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms and the ...

After a finite number of divisions, cells simply give up. As each round of replication trims their telomeres—the protective caps at the chromosome ends—those caps eventually become too short to ...

Ovarian cancer is the most lethal malignancy of the female reproductive system. Due to its insidious early symptoms and the absence of specific ...