Role of independent data-monitoring committees in randomized clinical trials sponsored by the National Cancer Institute. BTP patients encompass a heterogeneous group that can be classified into two ...

In a new set of guidelines, the U.S. Multi-Society Task Force on Colorectal Cancer offers various approaches to the diagnosis and management of cancer risk in patients with gastrointestinal ...

Systematic analysis of all newly diagnosed colorectal cancer for molecular features of Lynch syndrome will improve the identification of the syndrome Comprehensive analysis of the genes known to be ...

Personalized surveillance can help reduce the colonoscopy burden among patients with lower risk serrated polyposis syndrome, according to research published in Gut. Evelien Dekker, PhD, of the ...

The High Risk GI Cancer Clinic at Huntsman Cancer Institute is for people with a higher chance of getting gastrointestinal (GI) polyps and GI cancers due to genetic mutations or a family history of ...

Bethesda, Maryland (April 26, 2022) – Gastrointestinal hamartomatous polyposis syndromes are rare, hereditary disorders associated with an increased risk of colorectal cancer. The U.S. Multisociety ...

Juvenile polyposis syndrome, also known as familial juvenile polyposis, is a hereditary genetic syndrome. It is usually transmitted in an autosomal dominant fashion, but may be due to a new mutation ...

Simpson's Paradox and the Impact of Different DNMT3A Mutations on Outcome in Younger Adults With Acute Myeloid Leukemia We developed a decision model to evaluate NGS panel testing compared with ...

The use of next-generation sequencing panels that included highly penetrant genes associated with colorectal cancer and polyposis syndromes in addition to Lynch syndrome genes appeared to be ...

Juvenile polyposis syndrome (JPS) refers to a condition in which there are multiple benign polyps in the colon, or large intestine. Polyps are outgrowths occurring on the inside of a hollow organ. The ...