Leigh syndrome is the most genetically heterogenous phenotype of mitochondrial disease. We describe a patient with Leigh syndrome whose diagnosis had not been confirmed because of normal metabolic ...

Lactate is generated in the body as a byproduct, during normal metabolism and exercise. While considered a useless waste product for a long time, recent studies have shown that lactate can be an ...

Autoimmune diseases are a diverse group of conditions characterized by immune dysfunction that result in abnormal reactivity of B cells and T cells to normal components of the host. Autoimmune ...

Patients with paroxysmal nocturnal hemoglobinuria (PNH) had decreased quality of life (QOL) and worse fatigue that could be linked to lactate dehydrogenase levels. Researchers found that levels of ...

Higher levels of lactate dehydrogenase (LDH) at baseline were independently linked to an increased risk for heart failure (HF) events or cardiovascular death in patients with HF with reduced ejection ...

Elevated levels of lactate may lead to the development of cachexia (disease-related weight loss) following the onset of cancer, according to a study including data from mice and humans published in ...

Serum lactate levels of more than 4 mmol/L on admission to the intensive care unit (ICU) were associated with an increased rate of 60-day mortality in patients with acute kidney injury (AKI) receiving ...

Compare the diagnostic value of FLT and FDG PET/CT in assessment of regional lymph nodes in thoracic esophageal squamous cell carcinoma No significant financial relationships to disclose. This is an ...

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Elevated white blood cell counts also appear to correlate with shorter overall survival in patients receiving standard induction chemotherapy plus cytarabine for acute myeloid leukemia. High serum ...