Incorporating procalcitonin-guided decision making in the management of neonatal late-onset sepsis significantly reduced the ...

"Until meningitis is ruled out through lumbar puncture, septic very-low-birth-weight infants at high risk of mortality should receive empiric antimicrobials with high delivery through the blood-brain ...

A major multi-country study has found that WHO-recommended first-line antibiotics for neonatal sepsis are likely to be effective in only one-quarter of infections in low- and middle-income countries ...

The updated 2026 Surviving Sepsis Campaign pediatric guidelines offer 61 recommendations on infection control, hemodynamics, ...

Sepsis leads to life-threatening organ failure due to dysregulated host responses to infection and presents uniquely across age groups. Neonatal sepsis, affecting infants in their first 28 days, ...

Among the 981,869 children, 0.8% were diagnosed with sepsis and less than 0.1% diagnosed with meningitis; overall, 1.2% of children developed epilepsy during the study period. Children with clinically ...

BETA-hemolytic streptococci of Lancefield Group B have been implicated in human disease almost from the time when the precipitin-grouping technic first came into use. 1–3 Since that time additional ...

LISBON, Portugal — A shift toward broader-spectrum antibiotics and increasing antibiotic resistance has led to high levels of mortality and neurodevelopmental impacts in surviving babies, according to ...

To rapidly communicate information on the global clinical effort against Covid-19, the Journal has initiated a series of case reports that offer important teaching points or novel findings. The case ...

Despite the mortality and long-term sequelae occurring secondary to neonatal meningitis, past studies have shown that lumbar punctures (LPs) are not done in neonates as often as they should be. This ...