Wenzhou Medical University researchers have reimagined the spleen as a viable site for islet transplantation, enabling long-term diabetes control without the burden of full immunosuppression.

A combination of blood stem cell and pancreatic islet cell transplant from an immunologically mismatched donor completely prevented or cured type 1 diabetes in mice in a study by Stanford Medicine ...

This study is led by professor Tao Yang (Department of Endocrinology, the First Affiliated Hospital of Nanjing Medical University). The team generated islet cell type-specific (Gcg/α-, Ins/β-, and Sst ...

Mouse study success: Lab-grown insulin-producing islets normalized blood sugar in diabetic mice, showing consistent results across multiple human stem cell lines. Human trial hurdles: Clinical ...

Stanford scientists have taken a striking step toward reimagining type 1 diabetes treatment, using a carefully calibrated “immune reboot” to restore normal blood sugar in mice that had already ...

A substantial majority of diabetic mice transplanted with islets-plus-R-VECs regained normal body weight and showed normal blood glucose control even after 20 weeks -- a period that for this mouse ...

Advancing CNTY-813 as a potential functional cure in Type 1 Diabetes CNTY-813 iPSC-derived islet replacement therapy demonstrates durable in-vivo glucose control maintained for more than eight months ...

A pretreatment step could help transplanted pancreatic islets survive longer in patients with type 1 diabetes, according to a new preclinical study from Weill Cornell Medicine investigators. One ...