Scientists created a definitive E3 ligase atlas, resolving inconsistencies and enabling better disease research and drug ...

Researchers have found hundreds of metabolic enzymes attached to human DNA inside the cell nucleus. Different tissues and cancers show unique patterns of these enzymes, forming a “nuclear metabolic ...

Cornell researchers have developed a powerful new biosensor that reveals, in unprecedented detail, how and where kinases—enzymes that control nearly all cellular processes—turn on and off inside ...

Researchers at the Centre for Genomic Regulation (CRG) reveal that metabolic enzymes known for their roles in energy production and nucleotide synthesis are taking on unexpected "second jobs" within ...

Breast cancers (left) show higher nuclear levels of energy-producing enzymes than lung cancers (right), revealing tissue-specific nuclear metabolism. More than two hundred metabolic enzymes, many of ...

WEHI researchers have led a major global effort to create the first authoritative atlas for a class of enzymes that regulate almost every cellular process in the human body. Published in Cell, the ...