New research reveals how breaking down stored glucose (glycogen) in the brain may reduce toxic protein buildup linked to Alzheimer's disease, with dietary restriction showing promise.

Type 2 diabetes (T2D) has become one of the leading chronic diseases worldwide in terms of both incidence and mortality.

Glycogen, a hyperbranched polymer of glucose, plays a central role as an energy reserve across diverse organisms. In Escherichia coli, its biosynthesis is linked not only to energy storage but ...

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers ...

Published in Nature Metabolism, the research uncovers how breaking down glycogen-a stored form of glucose-in neurons may protect the brain from toxic protein buildup and degeneration.

Athletes must replenish glycogen in their muscles and liver after hard workouts, but doing so on a ketogenic or low-carb diet can be challenging. Here's why.

Gerty Cori was a biochemist whose work fundamentally reformed our understanding of how cellular energy is stored and released in the body.

Phosphatidylinositol 3-kinases (PI3Ks) are a family of enzymes that catalyze the phosphorylation of phosphatidylinositol at the D-3 position of the inositol ring, serving critical functions in ...

This dysregulation affects protein and glycogen synthesis and degradation. Sarcopenia also impacts energy utilization, leading to structural and functional dysfunction of skeletal muscle.

A surprising discovery about how brain cells handle sugar could shift how scientists approach dementia and Alzheimer’s treatments. In a new study published in Nature Metabolism, researchers ...