Much of the phenotypic variation that is observed within and between species is the result of differences in gene regulation: specifically when, where and how much the genes are expressed. Given the ...

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, ...

While scientists have known for more than two decades that all cells use a strategy called RNA interference to regulate gene ...

“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...

Genes undergo extensive editing through a process called alternative splicing, which greatly increases the size of the ...

It could be simply to control gene expression." The study, "Global impact of unproductive splicing on human gene expression levels and traits," was supported by funding from the National Institutes of ...

Our brain is arguably the organ that most distinguishes humans from other primates. Its exceptional size, complexity and capabilities far exceed those of any other species on Earth. Yet humans share ...

A new study finds the proteins responsible for controlling which genes are expressed in a genome do more than simply turn a gene on or off. Essentially, each type of protein that interacts with a gene ...

New Tapestri® assay measures both genotypic and transcriptional signals within individual cells, enabling researchers to map resistance, relapse, and lineage evolution across hematologic malignancies.