Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new study spanning known data about the neurotransmitter GABA and its principal receptors ...

Certain proteins found in the human brain have long been known to be critical to controlling how brain cells communicate with each other. So-called GABA A receptors are proteins that control the flow ...

F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have prepared and tested cyclopenta-thieno-diazepine derivatives acting as GABA-A receptor subunit α2β2γ1 positive allosteric modulators (PAMs). As ...

Scientists at Jiangsu Hengrui Pharmaceuticals Co. Ltd., Shanghai Senhui Pharmaceutical Co. Ltd. and Shanghai Shengdi Pharmaceutical Co. Ltd. have described benzene ring derivatives acting as GABA-A ...

A simple explanation of how alcohol interacts with GABA receptors in the brain, which can contribute to feelings of relaxation, slowed activity, and sleepiness.