Most tumors are made up of many different kinds of cancer cells, as shown in this pancreatic cancer sample from a mouse. Ravikanth Maddipati/Abramson Cancer Center at the University of Pennsylvania ...

Cancer does not develop overnight. It can take decades for cancer-promoting changes in the genome to eventually lead to the formation of a malignant tumor. Researchers at the German Cancer Research ...

EVOFLUx uses DNA methylation fluctuations as molecular barcodes to trace tumor evolution, offering insights into growth, treatment resistance, and prognosis. The method requires only bulk methylation ...

An enzyme that defends human cells against viruses can help drive cancer evolution towards greater malignancy by causing myriad mutations in cancer cells, according to a new study. The finding ...

The authors created detailed 3D renderings of tumors from more than 2,000 individuals, with breast, colon, pancreatic, kidney and uterine cancers, among others. From these detailed atlases, the ...

Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which ...

All of living nature is subject to evolution. Living organisms are exposed to selection pressure, which means that those that are best able to assert themselves survive. This natural selection process ...

Editor’s note: This is an automatically generated transcript. Please notify [email protected] if there are concerns regarding accuracy of the transcription. The breast cancer treatment landscape has ...

Marija Balic, MD, discusses how circulating tumor DNA assays for molecular residual disease detection have evolved in recent ...