A new technology allows scientists to map, in single cells, the DNA binding sites of transcription factors and other ...

Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, has been published in Nature Communications.

DNA methylation is a highly studied epigenetic modification that is involved in regulating genome function and plays fundamental roles in development and disease. 1 It is linked to a broad range of ...

In just a few decades, DNA sequencing technologies evolved from slow, manual processes to rapid, automated ones, making ...

DNA-based methods dominate molecular cancer diagnostics but struggle to detect gene fusions and assess splice site consequences. RNA sequencing enables sensitive fusion detection and direct assessment ...

Researchers at Harvard University have developed a semiconductor chip that can synthesize 64 different ...

Scaffolded DNA and RNA origami is a technique that allows scientists to build tiny, highly precise two- and three-dimensional ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Cambridge, MA - Traditional bisulfite sequencing damages DNA, while enzyme-based alternatives are inconsistent. A novel methylation analysis method, called UMBS-seq, was published this week in Nature ...