A new study from Washington University School of Medicine in St. Louis identifies a possible way to slow or block progression of age-related macular degeneration, a leading cause of blindness in ...

This depletion process ultimately relies on an enzyme called cathepsin A (CTSA). The researchers found that blocking CTSA ...

Cholesterol metabolism extends beyond its well-established role in membrane structure and steroidogenesis to become a pivotal regulator of immune function. Endogenous synthesis in the endoplasmic ...

Faulty lipid regulation in CLL patients impairs T-cell function, affecting treatment outcomes and resistance to current therapies. Differences in lipid metabolism between CLL patients and healthy ...

Cancer cells rewire cholesterol metabolism to support rapid proliferation, survival under stress and dissemination. Endogenous cholesterol synthesis via the mevalonate pathway and exogenous uptake ...

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson's disease in mice. Published in the ...

Since then, many scientists, including Lu, who now leads his own research group at Western University, have shown that PIN1 is overexpressed in different types of cancer and regulates many oncogenes ...

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*Important notice: bioRxiv publishes preliminary scientific reports that are not peer-reviewed and, therefore, should not be regarded as conclusive, guide clinical practice/health-related behavior, or ...

Cholesterol drugs side effects go beyond cholesterol. New research links statins to brain changes, weight gain, and lower ...

Start your day with this easy, make-ahead breakfast to support healthy cholesterol levels.

Researchers led by Zhentao Zhang at Wuhan University, China have discovered a cholesterol metabolite that plays a critical role in the development of Parkinson’s disease in mice. Published in the open ...