People who carry a high genetic risk for alcohol use disorder may have brain immune cells that respond differently to alcohol exposure, according to new research published in Science Advances. Using ...

Alcohol use disorder, which affects over 10% of Americans, can lead to persistent and serious insomnia. Difficulties falling asleep and staying asleep can last even after months of sobriety, ...

Excessive alcohol consumption causes alcoholic liver disease, and about 20% of these cases progress to alcohol-associated steatohepatitis (ASH), which can lead to liver cirrhosis and liver failure.

In addition to endodermal and mesodermal cells, alcohol causes changes in DNA methylation in ectodermal cells (in blue), from which the nervous system and brain develop. During the tightly regulated ...

Cell signaling is crucial for cells to communicate and function correctly. Disruptions in these pathways, caused by genetic mutations or environmental factors, can lead to uncontrolled cell growth, ...

A new study by Scripps Research reveals that alcohol dependence disrupts two signaling pathways in a stress-related part of the brain-and offers insights on developing drugs to treat this condition.