The study details the connection between SCARB2 deficiency and gastrointestinal dysfunction, revealing that the loss of SCARB2 leads to alterations in bile acid metabolism and dysbiosis in the gut ...
The VDR is a member of the steroid/hormone nuclear receptor superfamily that includes 48 ligand-activated transcription factors. [3] These factors bind to conserved elements in the promoters of genes ...
(A) Female and male body weight change over the course of 16 weeks for FXR hep flox/flox and FXR hep-/- (B) Female and male liver-to-body weight ratios; (C) H&E stained liver sections (n=3–6); (D) ...
This article highlights the ZenoTOF 8600 system's ability to detect, measure, and structurally describe bile acid levels in human plasma. Bile acid analysis in human samples has grown increasingly ...