The Houston Astros lost to the Seattle Mariners by a final score of 6-2 on Monday. The loss came after the team placed shortstop Jeremy Pena and starting pitcher Tatsuya Imai on the injured list before the game.

Josh Naylor hit his first two homers of the season and drove in five runs, George Kirby allowed two runs in 7 2/3 innings, and the Seattle Mariners completed a four-game sweep of the Houston Astros with a 6-2 win.

Jeremy Pena provided an update on his injury status after he was pulled early from the Houston Astros loss to the Seattle Mariners.

Houston finished its injury-filled road trip 1-9 after a four-game sweep in Seattle.

The Astros' slump deepens with their longest losing streak since 2013 as Houston struggles through a brutal early-season road trip.

These are the three biggest positives to a disappointing season's start.

The Houston Astros injury depleted roster took another hit on Monday.

SEATTLE (AP) — Houston Astros shortstop Jeremy Peña left Saturday night's 8-7 loss to the Seattle Mariners in the fourth inning because of right posterior knee tightness. Peña exited the game as a precaution and will get imaging done Sunday.

Seattle handled business the way contenders should, finishing off a four-game sweep of the battered Astros before a much tougher series in San Diego.

Mariners right-handed pitcher Bryce Miller has spent the entire MLB season on the injured list.