The Artemis II crew flew farther from Earth than any humans in history as they passed over the far side of the moon on Monday night.

NASA's Artemis II mission completes a critical engine burn, propelling the Orion spacecraft and its four-person crew out of Earth orbit toward the moon.

A screenshot from a NASA livestream shows Orion close to the Moon's surface, where all four astronauts, who have travelled farther than any human ever, set to record their observations. During this time, the spacecraft reached a maximum distance of 252,756 miles (406,771 km) from Earth, a new record for human spaceflight.

As NASA invites the public to follow the Artemis II mission as a crew of four astronauts venture around the Moon inside the agency’s Orion spacecraft, people around the world can pinpoint Orion during its journey using the Artemis Real-time Orbit Website (AROW).

The Artemis II crew will lose connection during their lunar observation. Here's when and how long it will last. (AP Photo)

As of 9:45 a.m., Orion was nearly 43,000 miles from Earth and 226,000 miles from the moon. The spacecraft was traveling at 2,100 mph. Here is a live video feed from the Orion spacecraft.

Orion's interior space is equivalent to that of two minivans, NASA says. That's a lot more breathing room than space capsules of the 1960s and '70s.

The first humans to travel around the moon in more than 50 years experience hours of scientific wonder — and moments of deep emotion.